For the first time, one of the new immunotherapy drugs has shown promise against breast cancer in a large study that combined it with chemotherapy to treat an aggressive form of the disease. But the benefit for most women was small, raising questions about whether the treatment is worth its high cost and side effects.Results were discussed Saturday at a cancer conference in Munich and published by the New England Journal of Medicine.Drugs called checkpoint inhibitors have transformed treatment o

ISTANBUL (AP) — Turkey will “never allow a cover-up” of the killing of Saudi journalist Jamal Khashoggi in Saudi Arabia’s consulate in Istanbul, a senior official in Turkey’s ruling party said Saturday, reflecting international skepticism over the Saudi account that the writer died during a “fistfight.”The comment was one of many critical reactions to Saudi Arabia’s announcement early Saturday of the writer’s violent death, indicating the kingdom’s efforts to defuse a scandal that has gripped th

ELKO, Nevada (AP) — President Donald Trump said Saturday he will exit a landmark arms control agreement the United States signed with the former Soviet Union, saying that Russia is violating the pact and it’s preventing the US from developing new weapons.The 1987 pact, which helps protect the security of the US and its allies in Europe and the Far East, prohibits the United States and Russia from possessing, producing or test-flying a ground-launched cruise missile with a range of 300 to 3,400 m

The United States and South Korea are scrapping another major military exercise this year, a Pentagon official said Friday, citing a push for diplomatic progress with North Korea. The top Pentagon spokeswoman, Dana W. White, said Washington and Seoul are suspending an air exercise known as Vigilant Ace "to give the diplomatic process every opportunity to continue.'' It was the latest move aimed at trying to nudge North Korea, which despises such US-South Korean exercises, into negotiating about

President Donald Trump will likely have his second meeting with Kim Jong -un early next year to continue charting a way for the North Korean leader to give up his nuclear weapons in a verifiable way.    A senior administration official told White House reporters Friday that a meeting is "likely sometime after the first of the year.''    The official spoke on condition of anonymity because details of the meeting have not been finalized.    US President Donald Trump. Yonhap   Earlier this month, S

President Vladimir Putin hailed new missiles in Russia’s military arsenals but emphasized Thursday that the country would only use its nuclear weapons in response to an incoming missile attack.He voiced confidence that Russia could resist Western pressure and expressed hope that U.S. President Donald Trump eventually would move to repair fractured ties with Russia. (AP)Speaking at an international policy forum in Sochi, Putin noted that Russia’s military doctrine doesn’t envisage a preventative

First lady Melania Trump toured a hospital’s neonatal care unit Wednesday to learn about the treatment given to newborns experiencing opioid withdrawal, after she was initially delayed by mechanical problems on her plane.Her flight was forced to return to a Washington-area military base because of smoke in the cabin, and she took a different plane to make the trip to Philadelphia. (AP)Mrs. Trump spoke briefly at a conference at Thomas Jefferson University Hospital on newborns who have been expos

 European Union leaders gave themselves several more weeks — perhaps until the end of the year — to clinch a friendly divorce with Britain before their separation, after a Brexit summit Wednesday avoided any friction but also produced no tangible results.British Prime Minister Theresa May provided none of the substantial new proposals that EU Council chief Donald Tusk had urged her to bring to the table, giving the 27 other leaders little more than a plea for goodwill. (AP)“The last stage will n

More than 2,000 Honduran migrants traveling en masse through Guatemala resumed their journey toward the United States on Wednesday as US President Donald Trump sought to turn the caravan into a political issue three weeks before midterm elections.A day after warning Central American governments they risk losing US aid if they don’t do something and saying that anyone entering the US illegally would be arrested and deported, Trump turned his sights on Democrats and urged Republican allies to camp

MOSCOW - Russia's top investigative body says it has identified the man who opened fire in a college in a Crimean town, killing 18 people and wounding more than 40. The Investigative Committee said an 18-year old student identified as Vladislav Roslyakov arrived at the vocational college in Kerch early Wednesday afternoon with a rifle and opened fire. The investigators said all the victims have died of gunshot wounds. The investigators had earlier put out a statement saying an improvised explosi

MOSCOW _ An explosive device killed 10 people and injured at least 50 others at a vocational college in Crimea Wednesday in what Russian officials called a possible terrorist attack. The National Anti-Terrorism Committee said in a statement that the blast at the college, in the city of Kerch in eastern Crimea, was caused by an unidentified explosive device. The committee's spokesman Andrei Przhezdomsky said sappers are inspecting the building for other explosive devices. The Tass news agency rep

Canada is now the largest country with a legal national marijuana marketplace as sales began early Wednesday in Newfoundland.And there was more good news for pot aficionados: Hours before a handful of retail outlets opened in the country’s easternmost province a federal official told The Associated Press that Canada will pardon all those with convictions for possessing up to 30 grams of marijuana, the now-legal threshold. (AP)A formal announcement was planned for later Wednesday. The official, w

The NASA astronaut who survived last week’s failed launch and emergency landing knew he needed to stay calm.Air Force Col. Nick Hague on Tuesday described the closest call of his career: His space capsule violently ripped from his damaged rocket shortly after liftoff, then with lights flashing and alarms sounding, plunged steeply back to Earth with punishing force.(AP)Hague said he and his commander, Russian Alexei Ovchinin, were flung from side to side and shoved back hard into their seats, as

A suspect identified by Turkey in the disappearance of Saudi journalist Jamal Khashoggi was a frequent companion of the kingdom's powerful Crown Prince Mohammed bin Salman, The New York Times reported Tuesday.Three other suspects are linked to Prince Mohammed's security detail and a fifth is a high-level forensic doctor, the Times said.(AP)The account could raise doubt about US President Donald Trump's claim -- after Saudi King Salman strongly denied to him any knowledge of what happened -- that